Search results for "recombinant LH"

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Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vi…

2007

Objective: To investigate the effects of recombinant (r-) LH supplementation in “low responder” patients undergoing ovarian stimulation with r-FSH for an IVF program. The apoptosis rate in cumulus cells was used as an indicator of oocyte quality. Design: Comparison of the rate of DNA fragmentation and caspase-3 activity in cumulus cells in women stimulated with r-LH and r-FSH, versus patients treated with r-FSH alone (control). Setting: In vitro fertilization (IVF) laboratory. Patient(s): Forty patients undergoing assisted fertilization programs treated with a GnRH agonist, or r-FSH treatment begun on day 3 of the cycle (control). In the r-LH group, from day 8 of gonadotropin stimulation, 1…

Adultendocrine systemmedicine.medical_specialtyPregnancy Ratemedicine.drug_classmedicine.medical_treatmentOvaryApoptosisDNA FragmentationFertilization in VitroBiologyOvulation InductionPregnancyInternal medicinemedicineIn Situ Nick-End LabelingHumansrecombinant LHOvarian follicleimplantation rateHuman cumulus cells; apoptosis; IVF; pregnancy rate; implantation rate; recombinant LH; oocyte qualityIn vitro fertilisationGranulosa CellsCaspase 3Obstetrics and GynecologyLuteinizing HormoneOocyteCumulus oophorusapoptosiRecombinant ProteinsPregnancy ratemedicine.anatomical_structureEndocrinologyHuman cumulus cellReproductive MedicineIVFFemaleoocyte qualityGonadotropinFollicle Stimulating HormoneLuteinizing hormonehormones hormone substitutes and hormone antagonistsFertility and sterility
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